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العنوان
Clinico-pharmacological Evaluation of phoxim Against Rhipicephalus sanguineus in Dogs /
المؤلف
Abd-Elaziz, Aliaa Ali Ibrahim.
هيئة الاعداد
باحث / علياء علي ابراهيم
مشرف / عبدالفتاح محمد عبدالفتاح
مناقش / مصطفي فايز محمد
مناقش / هشام يوسف محمد
الموضوع
Phoxim. Deltamethrin. Dogs.
تاريخ النشر
2022.
عدد الصفحات
92 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
8/3/2022
مكان الإجازة
جامعة قناة السويس - كلية الطب البيطري - فارماكولوجي
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study was designed to evaluate the acaricide efficacy of phoxim
and deltamethrin on Rhipicephalus sanguineus in vitro and to evaluate the efficacy of
both agents in vivo. In addition, we aimed to establish the current level of acaricidal
resistance for the two products commonly used in tick control in dog through: In vitro
studies including immersion tests (adult and nymph), larvae packet test and eggs
hatchability test. In vivo studies including evaluation of the efficacy of phoxim and
deltamethrin on Rhipicephalus sanguineus as well as its effect on hematological
parameters via twenty local dogs, that were divided into four groups of dogs, healthy
non- infested, infested non-treated, infested treated with phoxim and infested treated
with deltamethrin. The results of the present study indicated that the phoxim exhibited
significant elevation in mortality % with decreased in resistance % of Rhipicephalus
sanguineus adult compared to deltamethrin in both vitro and vivo studies. On the other
hand, deltamethrin exhibited significant elevation in mortality % with decrease in
resistance % of Rhipicephalus sanguineus nymph and larvae comparing with phoxim
in vitro results. Meanwhile, phoxim and deltamethrin showed significant decrease in
hatchability % of Rhipicephalus sanguineus eggs. Regarding to the blood parameters,
the infested group exhibited significant decrease and increase respectively, in
hemogram parameters and (WBCS count and eosinophiles %) compared to the healthy
control group. It could be concluded that the phoxim showed a powerful efficiency
against the Rhipicephalus sanguineus adult when compared with deltamethrin which
attributed to development resistance of adult stage for the latter in vitro and in vivo. On
contrary, deltamethrin showed better efficacy against Rhipicephalus sanguineus
nymph and larva compared with that of phoxim.