الفهرس 
Title : Clinical evaluation of topical melatonin application on implant stability of immediate dental implant in anterior & premolar region in systemically healthy patients (Randomized clinical trial)
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Abstract
Aim: Evaluate the effect of topical application of melatonin with immediate implant placement for better implant stability, soft tissue healing and post-operative pain versus immediate implant alone. Methodology: Twenty-four subjects with non-restorable anterior and premolar teeth indicated for immediate implant placement were divided into equal proportions between a study group (Immediate implant with melatonin) and a control group (immediate implant alone). Outcomes for implant stability were measured and recorded at baseline and after 6-months by Ostell, postoperative pain and soft tissue healing. Results: At the end of the study, a significant difference was shown in the mean of implant stability between the control group (59.5 ± 3.8) and the test group (68.0 ± 2.6) at p = 0.001. The test group showed a significant Soft tissue healing 2 (2-3) versus 3 (2-3) in the control group (p = 0.005). The median and range of the VAS scores were 7(6-8) for test group and 8(6-8) for control group with no statistically significant difference between both groups (p= 0.532) in day 0. Nevertheless, there were a statistically significant difference between test group and control group regarding postoperative pain in day 2 and day 7 after surgery