الفهرس 
Title: The Effect of Progressive Resistance Training on Fatigue in Multiple v Sclerosis Patients: A Systematic Review,Sclerosis Patients: A Systematic ReviewSclerosis Patients: A Systematic Review,
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Abstract
Background: Fatigue is a frequent complaint among multiple sclerosis (MS) patients, and it has adverse consequences on their life quality. It appears early in the disease course, can even appear before other MS symptoms. Progressive resistance training (PRT) could be a valuable method in the rehabilitation of MS patients. PRT may influence the body structure, fatigue scores, walking ability and the life quality of multiple sclerosis patients. Objectives: The objective of this current review was to assess the effectiveness of PRT for fatigue treatment in multiple sclerosis patients. Methods: The current study was conducted on multiple sclerosis patients aged {uF0B3} 18 years. The following five electronic databases: PubMed, Scopus, PEDro, Web of Science, and Cochrane Library were searched from 2010 to June 2021, as well as a manual search of bibliography. Randomized Control Trials (RCTs) were only included in this review and the others were excluded according to the eligibility criteria. The intervention used was PRT. Quality assessment of all eligible trials was done using the PEDro scale. Results: The results revealed that five studies fulfilled our inclusion criteria and were included in our meta-analysis. According to the PEDro scale, most studies were of good quality. The pooled analysis showed a statistically significant overall effect in fatigue outcome between the PRT group and the control group which was in favor of study group (SMD = -0.85, 95%CI = -1.58 to -0.11; p = 0.02). Conclusion: Progressive resistance training appears to be effective and safe in fatigue treatment in multiple sclerosis patients and patients should continue on PRT to maintain its positive benefits. But more future research is still required on this topic