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Abstract Purpose: to evaluate which is more effective resistance or aerobic exercises on cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy. Methods: Sixty breast cancer patients undergoing adjuvant chemotherapy who have cancer related fatigue and decreased immunity participated in this study. Their ages ranged from 30-60 years. The participants were selected from oncology department at Medical Research Institute in Alexandria and randomly distributed into two equal groups. group (A) received resistance exercises that can be achieved by using hand-held dumbbells, bottles of water, sand bags and body weight (3 times daily and five times per week) for shoulder flexion, abduction and horizontal adduction, elbow extension and flexion, calf raise, leg extension and squatting) time of exercise equal time of rest. Group(B) received aerobic exercises in form of running on treadmill (45 min five times per week). The study was conducted from December 2020 to March 2021. Results: It showed that Aerobic exercise was more effective than resistance exercises in improvement cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy. Conclusion: Aerobic exercise is valuable and effective method on cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy more than Resistance exercises |