الفهرس | Only 14 pages are availabe for public view |
Abstract Urinary tract infections (UTIs) currently rank among the most prevalent infectious diseases worldwide, with chronic and recurrent infections. Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in immune function in the mucous membranes. More IgA is produced in mucosal linings than all other types of antibody combined ; between three and five grams are secreted into the intestinal lumen each day.Secretory IgA can also inhibit inflammatory effects of other immunoglobulins. It was found that every change in sIgA levels may be associated with UTI. In all studied patients with UTI infection in both groups, the chief isolation percentage of bacteria was recorded for Escherichia coli (65.9 %), then Klebsiella pneumonia (13.6 %), then Pseudomonas aeruginosa (9.1 %), and coagulase positive staphylococcus (11.4 %). There was a significant decrease in IgA level in both patients with urinary tract infection (UTI) and patients with UTI and cancer in comparison with control group. There were non-significant differences in IgA level between patients with UTI and cancer and patients with UTI only. |