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Abstract Endoscopic DCR procedures were developed in the 1980s and 1990s. The endoscopic approach eliminates the necessity for a cutaneous incision and allows the surgeon to dissect and marsupialize the lacrimal sac more precisely. With success rates equivalent to the external technique, endoscopic DCR has gained favor as a treatment for nasolacrimal duct obstruction. Endoscopic DCR (endo-DCR) has the advantages of no external incision and scar, no disturbance of tear pump anatomy, and the capacity to examine, diagnose, and treat endonasal pathology like septal deviation or middle turbinate hypertrophy. The cost of instrumentation, the steep learning curve of endonasal procedures, and the difficulty of suturing the lacrimal sac-nasal mucosal flaps are all disadvantages of endoscopic DCR. Despite these drawbacks, success rates of up to 94 percent have been reported with enhanced instrumentation and technological developments. Ologen is a porcine collagen implant that is biodegradable and porous. It affects the fibrosis process by regulating secreted extracellular matrix deposition and influencing fibroblast migratory patterns. The purpose of this work is to compare the effectiveness of endoscopic dacryocystorhinostomy with ologen implant versus endoscopic dacryocystorhinostomy with silicon tube implantation. To the best of our knowledge this is the first paper to evaluate efficacy of ologen in endoscopic DCR, our result shows that endoscopic DCR with ologen implantation is not superior to endoscopic DCR with silicon stenting due to the challenging ologen |