الفهرس | Only 14 pages are availabe for public view |
Abstract Purpose is to evaluate the prognostic value of myocardial scar using cardiac magnetic resonance (CMR) in patients with ischemic cardiomyopathy (ICM) and non-ischemic cardiomyopathy (NICM). Methods; 154 patients with either ICM or NICM underwent CMR with late gadolinium enhancement (LGE) sequences for assessment of left ventricular ejection fraction (EF), detection and quantification of any myocardial scar using three methods; a) manual, b) number of segments involved, c) % of scarred myocardium. Patients were followed up for at least 6 months for clinical cardiac event. Results: Patients were divided into; group I; ICM (58%) and group II; NICM (42%). Clinical presentation was ranging from eventless (10%), chest pain (18%), heart failure (15%), hospitalization (35%), syncope (1%), ventricular tachycardia (<1%) and cardiac arrest (<1%). The scar mass was more in size in group I (17% ± 15) than in group II (8 % ± 13). Direct relationship was observed between scar size and event severity (P value < 0.001). Inverted relationship between LVEF and event severity in group I (P value of < 0.001) was detected but not in group II (P value 0.128). Conclusion: Myocardial scar size is a strong predictor for the clinical outcome in both ICM and NICM. EF is less reliable to predict morbidity in cardiomyopathy patients. |