الفهرس 
Oral manifestations of Leukemia
Chlorhexidine and prevention of oral diseaseOnly 14 pages are availabe for public view
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Abstract
Acute lymphoblastic leukemia (ALL) is the most prevalent malignancy in children. It is characterized by excessive and abnormal proliferation of primitive white blood cells with infiltration of the various tissues of the
body, especially bone marrow, spleen, and lymph nodes The nature and treatment of ALL can exert direct and indirect effects on the patients’ oral health. As leukemic cells can invade and enter the gums and deeper periodontal tissues leading to gingivitis, soreness, bleeding and infection in various oral tissues. Salivary amylase and total protein content in the saliva of leukemia patients are found to be elevated, and there was great association between arising of oral complication and high level of these proteins. Also disturbance in streptococcus count and salivary PH were noticed in leukemic patients that could increase risk of dental caries.So the aim of our study was to apply proper prophylactic agents to improve the level of salivary proteins and amylase, salivary PH and the count of streptococcus bacteria, subsequently enhance good oral hygiene and
decrease any oral complications. One of these agents, chlorohexidine varnish was applied to a group of leukemic children, while the other agent fluoride varnish was applied to another group of leukemic children, and the third group (control one) not received any type of these agents.