الفهرس | Only 14 pages are availabe for public view |
Abstract Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that can affect any organ and Lupus nephritis (LN) affects up to 60% of patients with systemic lupus erythematosus within 5 years of initial diagnosis with SLE. Ultrasound is a noninvasive and inexpensive imaging modality with sufficient anatomical details necessary to diagnose renal diseases without exposing the patient to radiation or contrast. This study was performed to assess the role of different ultrasound parameters in Lupus Nephritis patients (LN) which divide by renal biopsy into six lupus nephritis classes according to the 2003 International society of nephrology (INS)/Renal Pathology Society (RPS) classification. In our study our aim was to determine the relation between RI and Shear Wave Elastography and renal biopsy classification in Lupus Nephritis (LN). This study included 70 lupus nephritis patients with mean age (34.19 ± 9.675) and 20 normal subjects as control group with mean age (38.25 ± 9.182). In this study Creatinine level, Grey scale ultrasound and RI were measured for the 70 lupus nephritis patients and Shear Wave Elastography was measured for 35 patients of the 70 Lupus nephritis patients and renal biopsy was done as a gold standard. In our study we found a significant increase in the renal RI in Lupus Nephritis patients especially with advanced classes especially class III and IV compared to age matched healthy patients. |