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Abstract Diarrheal diseases are considered a Catastrophic problem globally, diarrhea has been listed as 1 of the top 10 causes of mortality and disability-adjusted life-years for persons in all age groups .Children are more affected than adults with peak of seasonal occurrence to Cryptosporidium . The BioFire FilmArray GI Panel tests stool specimens for common pathogens associated with gastroenteritis. Bacterial infections represent 78.0%, viral in fection represent 48.0% & Parasitic infection represents 34% and all infection in acute form. Quickly identifying the correct pathogen can ensure appropriate treatment, improve patient management, and help detect infectious gastroenteritis which can lead to severe illness or death (22 Targets in One Test). The advantages of using the BioFire FilmArray GI panel resulting in a significant reduction of unnecessary isolation days, antibiotic therapy and prevention of additional diagnostic procedures in patients with clinical suspicion of infectious gastroenteritis. Detection of cryptosporidium oocyst by Traditional microscopic methods (concentration &staining techniques) proved to be of great value for diagnosis and have high sensitivity and/or specificity as compared with BioFire FilmArray multiplex PCR GI Panel assay. On other hand, Detection of Giardia Lamblia oocyst by BioFire FilmArray multiplex PCR GI Panel assay proved to be of great value for diagnosis and have high sensitivity and/or specificity as compared with Traditional microscopic methods (Microscopic & concentration techniques). |