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العنوان
Potential Biological Effects of Gum Arabic on Kidney Disorders Induced by Arginine in Rats /
المؤلف
El-Sakoty, Samia Mhmoud Mohamed,
هيئة الاعداد
مشرف / Sara Ahmed Mohamed Sayed Ahmed
مشرف / Abeer Elsayed Hassan Elkhamisy
مشرف / Yousif Abd El-Aziz Elhassaneen
مناقش / shrief sabry mekawy
الموضوع
Liver functions. Glutathione.
تاريخ النشر
2021.
عدد الصفحات
154 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Multidisciplinary تعددية التخصصات
تاريخ الإجازة
20/1/2021
مكان الإجازة
جامعة بورسعيد - كلية التربية النوعية ببورسعيد - Home Economics
الفهرس
Only 14 pages are availabe for public view

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from 151

Abstract

Several decades ago, hude studies reported that recent pharmacological therapy is costly and associated with multiple side effects resulting in patient non-compliance. Therefore, there is a great need to search for alternative therapies particularly from natural sources as these are cost effective and possess minimal side effects. The present study will design to explore the biological effects of gum arabic (GA) on kidney disorders induced by arginine in rats. Also, the addition of GA to low protein diet (LPD), one of an important kidney disorders treatment, in a trial to add some positive biological effects to the kidney patients will be in the scope of this study. The obtained data revealed that The mean value of uric acid and creatinine of the negative control group fed on basal diet was 1.73 and 0,80 mg.dl-1 , while uric acid and creatinine of group fed on BD containing 2% arginine (Control +ve) was 2.91 and 1.79 mg.dl-1 , respectively. The rate of increasing in uric acid and creatinine as the result of kidney disorders induction was 68.28 and 124.15%. Additional of groups fed on GA and low protein diet (LPD) containing 2% arginine and led to decrease uric acid and creatinine by different rates . Co-treatment group fed on GA and LPD exhibited synergistic effect and recorded the highest decreasing rate in uric acid and creatinine (-19.99 and -21.15%, respectively). Also, the same behavior was recorded for serum mineral content (Na and K) and malondialdehyde content (MDA), the biomarkers of oxidative stress and inflammation in the body. In conclusion, we recommended to pay more attention in the future to carry out more research in the area of GA and extended its applications in human diets, industrial and medical applications such kidney diseases patients instead of the drugs/chemicals used which have induced healthy hazards, side effects and high coast for the human being.