الفهرس | Only 14 pages are availabe for public view |
Abstract ABSTRACT Background: Surgical site infections (SSI) in cesarean section can delay wound healing, impair cosmetic outcome and increase healthcare costs. Topical antibiotics are sometimes used to reduce microbial contaminant exposure following cesarean section. The current study will investigate the role of subcutaneous Fusidic acid instillation for prophylaxis against surgical site infection in cesarean section. Objective: A systematic review and meta-analysis of Subcutaneous fusidic acid instillation for prophylaxis against surgical site infection in elective cesarean section. A randomized controlled trial Data Sources: Medline databases (PubMed, Medscape, ScienceDirect. EMF-Portal) and all materials available in the Internet till 2018. Data Extraction: If the studies did not fulfill the inclusion criteria, they were excluded. Study quality assessment included whether ethical approval was gained, eligibility criteria specified, appropriate controls, and adequate information and defined assessment measures. Conclusion: Our study showed that with the use of subcutaneous fusidic acid before closing the skin in absorbable stitches, the infection rate was almost 6 times lower as compared to no fusidic acid before closing the skin. Therefore the use of subcutaneous fusidic acid instillation can be safely recommended for the prevention of wound infection (surgical site infection). |