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Abstract Regenerative endodontics with biologically based principles and regenerative protocols had replaced traditional apexification procedures. The present study aimed to evaluate the induction of root growth in nonvital immature permanent teeth with revascularization procedures. Materials and Methods: Sixty five permanent non vital immature teeth of 7-13 years old children with signs and symptoms of periapical pathosis were included in the study. Teeth were classified into two main groups according to the disinfectant material group 1, (triantibiotic paste) and group 2 (calcium hydroxide paste); each group was subdivided into two subgroups A and B (MTA or Glass ionomer) according to the sealing material. The disinfectant pastes were placed in the first visit and were removed in the second visit using 2.5% NaOCl irrigation, after root canal drying, apical bleeding was induced by over instrumentation in the apical region with 15 K-files. The sealing materials were placed in the coronal third of the root then composite restorations were placed in both subgroups. Children were followed up each three month up to 18 months clinically and radiographically. Standardized digital radiographs were evaluated for thickening of canal walls, continued root development and changes of periapical lesions. Data were collected and statistically analyzed using the Statistical Package for Social Science (SPSS) version 16. |