الفهرس | Only 14 pages are availabe for public view |
Abstract Head and neck cancer is a relatively common cancer worldwide and its treatment is highly complex and varies according to tumor location, accessibility, and extension to adjacent organs and tissues. Recurrence rate after treatment is common and when tumor recurs, it is usually difficult to recognize within deformed tissues or post-radiotherapy changes. Interpreting imaging studies of the neck after surgery or irradiation constitutes a challenge because of tissue alterations and variable appearances of recurrent tumors. Conventional MRI and CT have relatively low specificity and accuracy in differentiation between recurrence and post treatment changes. Several studies have demonstrated that diffusion-weighted and DCE MRI delivers promising results in differentiation between recurrent head and neck tumors and post treatment changes. The objective of this work was to assess the usefulness of DWI and DCE MRI for the differentiation between recurrence and post treatment changes in head and neck cancer. Patients with head and neck cancer who underwent surgical treatment and radiotherapy were referred from department of clinical oncology and nuclear medicine. Convectional MRI, DWI-MRI with calculation of ADC value and DCE MRI with analysis of the shape of the curve and the semi-quantitative parameters were done. Thirty patients were included in this the study, they were 16 males and 14 females with their ages ranged from 33-67 years). |