الفهرس | Only 14 pages are availabe for public view |
Abstract Background: The most important prognostic factor in squamous cell carcinoma of the head and neck (HNSCC) is the presence or absence of clinically involved neck nodes. The presence of metastases in a lymph node is said to reduce the 5-years survival rate by about 50%. The appropriate diagnosis of the presence of metastatic node is very important for the management of HNSCC Aim: To compare different diagnostic modalities for assessment of the clinically non palpable lymph nodes in HNSCC including by meta-analysis: CT, MRI, US, USFNAC and PET/CT for the proper cervical lymph node staging. Methods: Met-analysis study on patients with HNSCC of clinically non palpable lymph nodes (cN0). Results: Analysis was divided in 6 groups .Each group contain analysis of one modality according to available studies per patient, per level and per lesion .US is fair test per patient and per lesion. CT is good test per patient and excellent test per lesion. MRI is poor test per patient and fair test per lesion.CT-MRI combined is fair per patient and excellent per level. PET/CT is good per patient, fair per lesion and excellent per level. USFNAC is excellent per lesion. Conclusion: CT, CT-MRI combined, PET/CT and USFNAC proved to be excellent in detecting cN0. MRI was poor test in detecting cN0. US was a fair test in detecting cN0 if used alone |