Search In this Thesis
   Search In this Thesis  
العنوان
Using of Gum Arabic to Ameliorate Liver
Disorders Induced by Benzo(a)pyrene
in Rats /
المؤلف
Abe El-Aziz, Hoda Atef.
هيئة الاعداد
باحث / هدي عاطف عبدالعزيز
مشرف / عبير نزيه أحمد عبد الرحمن
مناقش / شريف صبري رجب
مناقش / محمد سمير الدشلوطي
الموضوع
Liver - Diseases - Popular works. Liver Diseases - Popular works.
تاريخ النشر
2020.
عدد الصفحات
130 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
اقتصاد منزلي
تاريخ الإجازة
3/3/2020
مكان الإجازة
جامعة المنوفية - كلية الإقتصاد المنزلى - قسم علوم التغذية وعلوم الأطعمة
الفهرس
Only 14 pages are availabe for public view

from 130

from 130

Abstract

This study was carried out to evaluate the effects of Gum Arabic
(GA) in liver functions of rats treated with benzo(a)pyrene
(B(a)P).Thirty male mature albino rats weighted 130-150g per each,
were used in this study and divided two main groups, the first group
(group 1, 5 rats as a negative control group) still fed on basal diet and
injected with the vehicle alone (5 ml/kg body weight), while the other
main group (25 rats) was were challenged with an ip injection of B[a]P
(100 mg/5 ml/kg body weight) dissolved in 0.9% NaCL solution
containing 0.1% Tween 20 to induce liver impaired. The tested plant
powder were given to the rats as a percent of 1,2,3 and 4% from the
basel diet for 28 days. At the end of the experiment,Glotamic oxalic
transaminase (AST), Glotamicpyrofic transaminase (ALT), alkaline
phosphatase (ALP), GSH was determined by HPLC , Liver glycogen
levels determined after digestion of liver and precipitation of glycogen
by glycogen assay kit II, lipid peroxide levels measured as
malondialdehyde in serum and liver were determined as thiobarbituric
acid reactive substances (TBARS). According to the results, Gum Arabic
(GA) could be used for improvement of liver functions and the best
treatment was for group 6 (treated with 4% GA powder).