الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Systemic arterial hypertension is a long-term condition in which the blood pressure is persistently elevated. It is defined as a systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. The primary response of the retinal arterioles to systemic hypertension is vasoconstriction. Sustained hypertension leads to disruption of the inner blood retinal barrier, increased vascular permeability & arteriolosclerosis. The fundus shows focal and generalized arteriolar narrowing, micro-aneurysms, flame shaped hemorrhages, cotton-wool spots, hard exudates & optic disc swelling.Optical Coherence Tomography (OCT) is a non -invasive, reproducible and reliable method for diagnosis of retinal pathology. It has allowed detailed quantitative analysis of retinal microstructure with high spatial resolution.It provides a significant tool for the diagnosis, prognosis, and management of systemic hypertension in clinical practice.The aim of this study was to investigate changes in peri-papillary RNFL and macular thickness in patients with systemic arterial hypertension compared to normotensive control eyes using with Spectral Domain Optical Coherence Tomography (SD-OCT): TOPCON 3D OCT-2000 device.This retrospective cohort study was done at Benha university hospitals from November 2018 to August 2019. This study included “40 eyes” of adult hypertensive patients (age 53.75 ± 6.60 years) without any other systemic or ocular disease. The control group included “20 eyes” of age-matched participants (54.0 ± 7.86 years) with normal blood pressure. Mean duration of hypertension was 7.07 ±1.68 years. The obtained results of our study showed that peri-papillary RNFL thickness was thinner at superior, inferior, nasal, temporal parts of RNFL and average total RNFL thickness at hypertensive patient eyes group compared to normotensive control eyes group (p<0.001 for all except