الفهرس | Only 14 pages are availabe for public view |
Abstract Asthma is a common, chronic respiratory disease affecting 1–18% of the population in different countries. Zinc status may be detected by factors as dietetic assessment, serum zinc level, stunting data, anemia prevalence and other indicators. Zinc has been supposed to have anti-oxidant, anti-apoptotic, anti-inflammatory and anti-allergic effects, so zinc deficiency is suspected to play a role in the pathogenesis, control and severity of bronchial asthma.The aim of our work was to study the relationship between zinc status and childhood asthma, whether atopic or non-atopic, as well as the relation between zinc status and the severity and level of control of the disease.The present study took place from April 2017 to December 2018 in the Pediatric and Clinical Pathology Departments of Benha University Hospital. It included 90 children, 5-12 years of age. Sixty of them were suffering from bronchial asthma and the other 30 were healthy age and sex matched children taken as a control group. Both sexes were included.After taking informed verbal consents from the parents, the patients were divided into the following two groups:group I: included 30 children with atopic asthma, 19 (63.3%) males and 11 (36.7%) females. Their ages ranged from 5 to 12 years with a mean age of 8.6±1.9 years and 53.3% of them were living in rural areas.group II: included 30 children with non-atopic asthma, 11 (36.7%) males and 19 (63.3%) females. Their ages ranged from 5 to 12 years with a mean age of 8.3±1.8 years and 43.3% of them were living in rural areas. |