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العنوان
Evaluation of Blood Neutrophil Lymphocyte Ratio (NLR) & Platelet Lymphocyte Ratio (PLR) As Inflammatory Biomarkers in Childhood Asthma /
المؤلف
Ibrahim, Mostafa Mohammed.
هيئة الاعداد
باحث / مصطفى محمد إبراهيم
مشرف / شيرين محمد عبد الفتاح
مشرف / ماهيتاب مرسي حسين
مشرف / شيماء عبدالمليك بيصار
تاريخ النشر
2019.
عدد الصفحات
121 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 121

from 121

Abstract

Background: It is shown that neutrophil to lymphocyte ratio (NLR) as an indicator of inflammation) measured in peripheral blood has a contribution in the determination of diagnosis and prognosis in numerous diseases. This study investigated the correlation between asthma control status and NLR in asthmatic children and asthma phenotypes according to their sputum cytology.
Patients and Methods: a Case control study on 60 asthmatic children, 10healthy subjects were included in the study. Respiratory function tests (RFT) was applied to the patients. Level of control was assessed with the asthma control questionnaire (ACQ). The difference between patients groups and control groups in terms of NLR was examined.
Results: The median NLR was 1.32 (1.12-1.6) in the patient group and 0.71 (0.4425-1.125) in the control group. The difference was statistically highly significant (p=0.003). Also, median NLR was 1.32 (1.12-1.6) in the patient group and 0.71 (0.4425-1.125) in the control group.
Conclusion: NLR was higher in patients with asthma compared to control group. Also as the asthma control status worsened, NLR increased. We think that NLR can be guiding in asthmatic.