الفهرس | Only 14 pages are availabe for public view |
Abstract Summary chronic, pulmonary infections remain the single most prominent cause of the increased morbidity and mortality in chronic chest lesions (CCL), Anaerobic bacteria are relatively frequent pathogens in pulmonary infections including aspiration pneumonitis, lung abscess, necrotizing pneumonia and empyema. Anaerobic bacteria are the most overlooked bacterial pathogens of the lower respiratory tract. They are often infrequently recovered from this site probably because of improper specimen collection and lack of appropriate anaerobic identification techniques. Anaerobic microorganisms are now widely accepted as significant pathogens in human diseases, as such, the proper diagnosis and treatment of these infections are important healthcare priorities. The Frequency of anaerobic isolates among all patients under the study was 26%, aerobic isolates were 80% and the fungal isolates were 33%. The most common isolated anaerobes were: 7 Prevotella (35%), 4 Lactobacillus (20%), 4 Veillonella (20%), 3 Propionibacterium (15%), 1 Peptostreptococcus (5%) and 1 Fusiobacterium (5%). The anaerobic isolates were sensitive to meropenem. Regarding Amoxicillin/clavulanic all isolates were sensitive to this drug except one Prevotella isolate. Prevotella and Propionobacterium isolates showed 57.2% and 33.3% resistance to clindamycin respectively. As regards the resistance of the isolates to metronidazole was variable, 15% for Prevotella , 75% for Lactobacilli and 100% for Probionobacterium. As regards the isolated fungi, 33 isolates out of the 100 studied samples (33%). C. albicans was the most common isolated organism(66.7%) while C. non albican were isolated from 30.3% of cases and only one Aspergillus niger isolates(3%). Regarding the antifungal susceptibility, all Candida isolates were susceptible to amphotericin B. One C. albicans isolate was resistance to Fluconazole 4.5% while C. non albicans isolates showed 30% resistance to Fluconazole. C. albican isolates showed 9% resistance to voriconazole while C. non albicans isolates showed 30% intermediate resistance to voriconazole. Resistance of the Candida isolates to Flucytosine was variable, C. albican showed 4.5% resistance and 4.5% intermediate resistance to Flucytosine. C. non albican showed 20% resistance and 10% intermediate resistance to Flucytosine. |