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العنوان
Short-term Effect of Blood Pressure Variability on Outcome of Acute Myocardial Infarction /
المؤلف
Mohamed, Maha Abd Elbaky.
هيئة الاعداد
باحث / مها عبدالباقى محمد
مشرف / طارق محمد عبدالرحمن
مشرف / عمرو صلاح أمين
الموضوع
Cardiology.
تاريخ النشر
2018.
عدد الصفحات
83 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة المنيا - كلية الطب - قسم القلب والأوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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Abstract

BP is characterized by important variability in healthy subjects within 24 hours, as an adaptative mechanism to emotional stimuli or physical activity. Increased BP variations within the 24 hours (over seconds, minutes and induced by circadian rhythm) is considered “short term BP variability”. Variations in BP were also described over longer periods of time, between days, weeks, months, seasons or even years. This fluctuation of BP was named “long-term BP variability.
The aim of our study was to detect the Impact of Blood pressure variability on short term cardiovascular outcome of acute myocardial infarction.
This study enrolled 266 patients who suffered acute STEMI and were admitted in the department of Cardiology, Minia University hospital and Minia Health Insurace hospital during the period from May 2015 to May 2017.
All patients were subjected to the following:
1. History taking.
2. Clinical examination.
3. Twelve leads ECG.
4. Transthoracic echocardiography.
5. Biochemical analysis for Renal function and random blood glucose.
6. Ambulatory blood pressure monitoring (ABPM) to calculate blood pressure variability indices as Standard Deviation (SD) and Average Reading Variability (ARV).
All patients were followed up weekly for 1 month After CCU discharge successfully .
1- Patients were classified into two groups according the presence or absence of primary and secondary end points. Primary end point included (all cause mortality and rehospitalization for heart failure) while Secondary end point included ( cardiac death and rehospitalization for heart failure , ischemia or arrhythmias ).
The study demonstrated that:
Dipping status was the most significant parameter of the blood pressure variability indices in prediction of the primary end point while other blood pressure variability indices ( SD and AVR ) showed no statistically significant difference between both groups.
Ejection fraction (EF) was the most significant parameter in prediction of primary and secondary end points.