الفهرس | Only 14 pages are availabe for public view |
Abstract In our study we determine whether platelet-rich plasma (PRP) injections are associated with improved pain and function scores when compared with corticosteroid injections for plantar fasciopathy. Methods: This systematic review consisted of 6 steps, including a systematic search of the literature (PubMed, SCOPUS, Web of Science, and The Cochrane Library), selection of studies, recording of study characteristics, assessment of methodological quality and bias. and extraction of data on clinical outcomes and their comparisons between different groups, then meta analysis. Results: After exclusions, 19 studies were included in the final meta-analysis incorporating data on 911 unique patients (PRP Group=496, steroid=390) between the years 2007and 2017. The mean age of included patients in the PRP group ranged from 30.7 to 51.0 years compared with 33.9–59.0 years in the steroid group. Conclusion: PRP injections are associated with improved pain and function scores at three month follow-up when compared with corticosteroid injections. Information regarding relative adverse event rates and cost implications is lacking. Further, large-scale, high-quality, randomised controlled trials with blinding of outcome assessment and longer follow-up are required. |