الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 275 |  |  |
| | | from | 275 | | |
Abstract
Background: Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for several hematological malignancies, bone marrow (BM) failure syndromes, and some inherited metabolic disorders. An adequate number of nucleated or CD34 cells in the graft are of utmost importance to achieve sustained engraftment and good survival. Aim of the Work: to assess CD34 in Egyptian patients with AML subjected to allogeneic peripheral blood stem cell transplantation and its relation to level of chronic graft versus host disease in the time period from January 2013 to December 2016. Patietns and Methods: This retrospective study included 141 patients presenting to Bone Marrow Transplantation Unit at Nasser Institute Hospital from January 2013 to December 2016 they are adult patients between 19 to 58 years old with Acute Myeloid Leukemia treated by allogeneic peripheral blood stem cell transplantation (PBSCT) at Nasser Institute. Results: The revealed no statistically significant difference between Patients with low or high CD34+ cell count as regards the incidence of Graft Versus Host Disease (GVHD), chronic Graft Versus Host Disease (cGVHD), relapse or mortality (p-values >0.05). Conclusion: In our study we have found that there was a significant relationship between CD34+ cell count and engraftment of platelets till it reaches 100000 and there wasn’t a significant relationship with incidence of cGVHD.