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العنوان
Histopahologic Assessment of Colonic Polyps in Patient Presenting to South Egypt Cancer Institute /
المؤلف
Mohamed, Israa Mostafa Kamal.
هيئة الاعداد
باحث / إسراء مصطفي كمال
مشرف / عبد الهادي محمد محمد عمر
مناقش / اعتماد حلمي يس
مناقش / حسين عبد المنعم حسن
الموضوع
Colon Cancer.
تاريخ النشر
2017.
عدد الصفحات
71 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأورام
الناشر
تاريخ الإجازة
10/7/2018
مكان الإجازة
جامعة أسيوط - كلية الطب - Pathology
الفهرس
Only 14 pages are availabe for public view

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Abstract

This is a retrospective study ; 74 formalin fixed paraffin embedded blocks were included in our study, obtained from the Archives of Pathology Department of South Egypt Cancer Institute. All cases were examined by two pathologists, using World Health Organization (WHO) criteria were applied to assess the grade of dysplasia and architecture of the polyps.
Adenomatous polyps were divided into low-grade or high-grade dysplasia. Depending on the presence and volume of villous configuration, and accordingly adenomatous polyps were further classified as tubular, tubulovillous or villous. The presence of various degrees of inflammatory infiltrate, ulceration, edema and granulation tissue were the criteria on the basis of which the diagnosis of an inflammatory polyp was made. The clinical and demographic data were obtained from Archive of Pathology Department Lab in South Egypt Cancer Institute.
In this study, Male predominance was observed with 31.6 years old is the mean age of incidence of colorectal polyps. Regarding colon polyp type , our study showed that non adenomatous polyps were more prevalent than adenomatous polyps comprising 70.6%, while adenomatous polyps account 29.4%
Regarding site and size of colorectal polyps, The rectum and right colon were common site of incidence of colonic polyps.
Most of our cases ranged from 1-2 cm in size represent > 50% , followed by small size < 1cm, Adenomatous polyps were ranged from 1-2 cm and tubulovillous type was commonest, while most of non adenomatous polyps ranging from 1-2 cm was hamartomatous type.
In our study there was significant association between different colon polyp type and patient age, As non adenomatous polyps show most of hamartomatous polyps occur in young age, while adenomatous polyps showed that tubulovillous adenoma was common in age group of 40-60.
According to degree of dysplasia, most of adenomatous polyps showed high grade dysplasia, which was common in females than males. However there was no significant association between dysplasia and polyps size.