الفهرس | Only 14 pages are availabe for public view |
Abstract Infertility affects 10-15% of couples. Male factor is responsible for 60 % of cases and oligospermia represents about 34.14% of infertile males. Kisspeptin is a relatively newly discovered hormone. The studies point to its role in regulation of HPG axis. Its role in infertility disorders is still too much obscure. We aimed by this study to clarify the role of kisspeptin in severe oligospermia. To approach our goal, we selected 22 severe oligospermic males (patient group) and another 22 normal fertile age matched males (control group) to compare between them. In addition to thorough history, clinical examination, semen analysis; we measured serum FSH, LH, prolactin and total testosterone as well as serum kisspeptin levels. Statistical analysis of results showed that: 1. Both groups are age matched. 2. There is no significant diffference regarding testicular volume in both groups. 3. There are no significant differences regarding serum FSH, LH, prolactin & total testosterone levels in both groups. 4. Kisspeptin is significantly lower in the severe oligospermic patients compared to the fertile males. 5. No correlation between kisspeptin & FSH, LH, prolactin and testosterone. |