الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Gait and balance impairment in patients with Parkinson syndromes have proved to be difficult to treat. As a result, there has been a drive towards non-pharmacological therapies. At present, tDCS offers a safe, and easy-applicable method of non-invasive brain stimulation, and there are now several published tDCS trials on patients with hypokinetic gait disorders, aimed at improving various clinical aspects especially those resistant to dopamine as gait and posture Methods: case-controlled, randomized trial, to assess the efficacy of (Cz) anodal tDCS in 100 patients with hypokinetic gait disorders who were randomized equally into case (received active tDCS stimulation and physiotherapy) and control (received sham tDCS stimulation and physiotherapy) groups. Results: We found significant difference in favor of non_IPD patients in case group as regards percent of improvement in GARS_M at 4 wks (p= 0.04). Yet other parameters showed no significant difference There was significant difference in favor of IPD case group in percent of improvement in ADL at 4 wks (p=0.04), GARS_M at 8 wks (p=0.039), with tendency for significance in GARS_M at 4wks. Conclusion: t DCS -as a method of non-invasive brain stimulation technique - showed a potential role in enhancing the effect of physiotherapy for gait rehabilitation among hypokinetic gait disorders. Also, these results could highlight the promising role of our suggested new site of stimulation (Cz) to ameliorate the gait impairment in such patients. |