الفهرس 
Carbon Monoxide PoisoningOnly 14 pages are availabe for public view
 |  | from | 204 |  |  |
| | | from | 204 | | |
Abstract
Introduction: Carbon monoxide (CO) is an odorless, colorless, tasteless, non-irritating gas formed as a by-product of burning organic compounds. The affinity of hemoglobin for CO is 200 to 250 times greater than its affinity for oxygen. This results in competitive inhibition of oxygen release due to a shift in the oxygen-hemoglobin dissociation curve, reduced oxygen delivery, and subsequent tissue hypoxia.
Aim of the Work: This study aims to assess the role of human fatty acid binding protein as an early predictor biomarker for carbon monoxide induced cardiotoxicity among patient admitted to the Poison Control Center Ain Shams University Hospitals.
Patients and Method: A prospective observational study was conducted beginning from November 2015 to April 2016 for adult (18-65years old) patients with history of acute moderate and sever carbon monoxide intoxication of both sex, admitted to PCCASUH. 25 patients were included in this study according to sample size determined by statistical specialist at community medicine and environmental department, faculty of medicine, Ain Shams University.
Results: group 1 (moderately intoxicated cases):
All patients diagnosed as acute moderate CO poisoning who were seven patients (28%) of all patients.
group 2 (severely intoxicated patients):
All patients diagnosed as acute severe CO poisoning who were eighteen patients (72%) of all patients.
Conclusion: from the current study it was concluded that identification of the degree of cardiac injury is essential in patients admitted and followed-up with the diagnosis of CO intoxication. ECG, cardiac enzymes, and even echocardiography should be performed in the ED on these patients to determine the level of injury.