الفهرس 
Introduction& Aim of the workOnly 14 pages are availabe for public view
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Abstract
The present study conducted at Minia Children University Hospital PICU Unit, during the period from February 2015 to October 2015.
This study was a case control study included 30 critically ill children were evaluated as critically ill children, follow up prognosis with PRISM III score (Karambelkar et al., 2012), in addition to 30 apparently healthy children as a control group.
All cases were subjected to complete medical history, complete physical examination, laboratory investigations (including zinc, iron and magnesium) and PRISM score.
The age group of our studied cases ranged from (12 months, 30 months), with Mean ±SD (21.5±9.9), 56.6%males and 43.3% females.
In the current study respiratory system illnesses were the most common diagnosis (30%), followed by central nervous system affection (26.7%) and sepsis (23.3%).
Number of cases were required mechanical ventilator is 20 (66.6%), Mortality rate was 76.6% (23cases).
Duration of stay in ICU, sepsis, MODs on admission and use of mechanical ventilator were significant risk factors for death with P value (<0.001, 0.004, 0.006, and <0.001) respectively.
Zinc, iron and magnesium levels were significantly lower in all critically ill children than in controls (p<0.001).
Significant negative correlation was found between zinc, iron and magnesium blood level and PRISM III (P=0.003,0.008,0.008) respectively, which reflect that increase in PRISM III score is associated with a relevant decrease in the serum zinc, iron and magnesium levels.
PRISM III score was significantly higher in patients who died than survived (p =0.003*).
Significant relation between the PRISM score and the outcome (p< 0.003). A PRISM score >8 was associated with a poor outcome with a sensitivity at 87.5% and specificity at 83.3%.