الفهرس | Only 14 pages are availabe for public view |
Abstract Abstract Background: ADHD is a common neurodevelopmental disorder in children. Abnormal EEG findings with no clinical epilepsy is a common finding in ADHD as compared to normal children. The aim of this study was to assess the efficacy and tolerability of carbamazepine (CBZ) in ADHD children who have abnormal EEG findings. Methods: 15 drug naïve ADHD children (13 boys, 2 girls; mean age, 6.62 years; range 4-10) with EEG abnormalities but no clinical seizures were included. All were treated with carbamazepine (mean dose 5 mg/kg/day). They were followed up through a period of 8 weeks for symptom improvement and occurrence of side effects. Improvement was measured using the parents form ADHD rating scale 4; before and after CBZ treatment. Results: there was statistically significant improvement in mean ADHD RS scores specifically in the domains of inattention and combined symptoms while there was no improvement in hyperactivity scores. Conclusion: low dose carbamazepine can be a well tolerated and effective treatment in some cases of ADHD associated with abnormal EEG findings. Key words: Attention deficit hyperactivity disorder, carbamazepine, electroencephalography, ADHD rating scale |