الفهرس 
Glucose metabolismOnly 14 pages are availabe for public view
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Abstract
Background: Glucose concentration in plasma is normally preserved within a narrow range reflecting a balance between the utilization and production of glucose. Postprandially, carbohydrates from diet serve as the principal external source of glucose. Diabetes Mellitus (DM) is a group of metabolic disorder of numerous etiology characterized by hyperglycemia and glucose intolerance. The condition arises from the metabolic disturbance of carbohydrate, fat and protein caused by imperfection in insulin release, insulin action or both.
Thirst, blurring of vision, polyuria, and loss of weight are the general symptoms of DM. Diabetic Ketoacidosis (DKA) is a life-threatening complication of type 1 diabetes mellitus but it is not uncommon in some patients with type 2 diabetes and needs to be treated as a medical emergency.
DKA is associated with a significant morbidity and mortality and must be diagnosed promptly and managed intensively. DKA is a complex disordered metabolic state characterised by ketonemia, hyperglycemia and metabolic acidosis.
Aims: This essay will discuss current concept about updated guidelines for diagnosis and management of adult diabetic ketoacidosis.
Conclusion: Insulin and glucagon are potent regulators of glucose metabolism. For decades we have viewed diabetes from a bi-hormonal perspective of glucose regulation. Complications of treatment include hypoglycemia, hypokalemia, hypoxemia and rarely pulmonary oedema.