الفهرس 
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Abstract
This prospective study was conducted at sleep disordered breathing (SDB) unit, Mansoura University Hospital. This study carried out on fifty patients for the investigation of symptoms suggestive of OSAHS during the period from July 2014 to March 2015. Aiming to determine the sensitivity and specificity of overnight oximetry as a screening tool for obstructive sleep apnea hypopnea syndrome and to compare the sensitivity and specificity of overnight oximetry to Berlin questionnaire and STOP-Bang questionnaire in sleep disordered breathing unit, chest department; Mansoura University Hospital; Egypt. In this study; among the 50 cases studied, the mean age was 45.80±10.97, 30 patients (60%) were men and 20 (40%) were women. The mean value of BMI was 39.53 ± 8.60 kg/m2. The mean value of NC was 43.99 ± 4.48 and FEV1/FVC% was 89.48 ± 10.84. The prevalence of OSAHS in studied cases was 80% (40 out of 50) with OSAHS of which 24% (12 out of 40) with mild OSAHS, 16% (8 out of 40) with moderate OSAHS and 40% ( 20 out of 40) with severe OSAHS. While 20% (10 out of 50) without OSAHS. There was significantly higher prevalence of OSAHS among male than female. There were significantly higher NC, Stop-bang questionnaire, Epworth sleepiness scale and Berlin questionnaire among OSAHS patients than non OSAHS patients. On the other hand, BMI and age among OSAHS patients were insignificantly higher than non OSAHS patients. The polysomnographic parameters revealed that there were significantly higher AHI, ODI, total arousal and Spo2 time < 90% among OSAHS patients than non OSAHS patients, but minimal Spo2 was significantly lower among OSAHS patients than non OSAHS patients, while there was no significant difference as regard baseline O2 saturation. As regard polysomnographic parameters; there were significantly higher AHI, ODI, total arousal and Spo2 time < 90% among severe OSAHS than non-severe OSAHS patients but minimal Spo2 was significantly lower among severe OSAHS patients than non-severe OSAHS patients, while there was no significant difference as regard baseline O2 saturation. Overnight pulse oximetry parameters showed that there were significantly higher ODI and significantly lower minimum Spo2 among OSAHS patients than non OSAHS patients, while there was no significant difference as regard basal Spo2. Conclusion: Stop-bang questionnaire is a valid questionnaire with a high sensitivity which increases with severity and can be used as a predictor for early diagnosis of OSAHS. Overnight pulse oximetry is an inexpensive method for screening of OSAHS patients with high sensitivity, specificity and accuracy increased with severity.