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Abstract Lead is a common industrial and environmental pollutant. Prolonged exposure of a sub lethal dose to this toxicant is associated with oxidative stress and considered to be a risk factor for kidney, liver added to many disorders. This study was carried out to investigate the most toxic effects of lead with trial to diminish this toxicity by supplementation of date extract. Therefore, one hundred and twenty mature male albino rats were used. They divided into four equal groups, 30 rats of each. group 1 was considered as control. Rats of group 2 were supplemented lead acetate at a dose of 5mg/kg body weight in drinking water for 3 months. Rats of group 3 were given lead acetate at concentration of 2 mg/kg body weight, while in group 4 date extract is mixed with lead acetate at concentration of 2mg/kg body weight and given to rats for12 weeks. |