الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Diabetes mellitus is the most common endocrine metabolic disorder in childhood and adolescence. Type 1 diabetes accounts for 5-10%, while type 2 diabetes accounts for 90-95% of those with diabetes.
Long term complications of DM are the challenges associated with diabetes and they include diabetic neuropathy, nephropathy, retinopathy, atherosclerosis and ischemic heart disease.
Impairment of growth may be one of the complications of chronic diseases. Type 1 DM like other chronic diseases, may have negative effects on growth and final height of cases with a disease onset during childhood or adolescence. It is not clear if the growth is only affected by metabolic control of DM or if other contributing factors also exist.
The present study aimed to study the relation between glycemic control and growth status in children with type 1 DM.
Fifty children aged from 5 to 18 years old with type 1 DM of 3 years or more duration of disease were included in the study. We excluded children with evident organ system disease or receiving drugs known to affect growth. Children included in the study were subjected to full history taking, thorough clinical examination, anthropometric measurements (Weight, Height and BMI) and laboratory investigations including glycosylated hemoglobin.
The present study showed that 30 percent of our diabetic children were short (13 cases) or very short (2 cases), all of these patients had poor glycemic control based on mean HbA1c with strong significant negative correlation between mean HbA1c and Ht standard deviation score.
In addition there was no significant relationship between the glycemic control and the BMI percentiles but all the overweight and obese cases of this study were poorly controlled.
There was a statistical significant relationship between the age of cases, duration of diabetes and glycemic control.
from this study, it was concluded that linear growth in children and adolescents with type 1 DM may be affected by glycemic control, overweight and obesity are more common in uncontrolled cases than controlled cases of type 1 DM
It is recommended that tight glycemic control in children and adolescence with type 1 DM and careful monitoring of weight and height are important in the prevention and delaying the occurrence of diabetic complications.