الفهرس 
Aim of the WorkOnly 14 pages are availabe for public view
 |  | from | 32 |  |  |
| | | from | 32 | | |
Abstract
Awareness of respiratory muscle strength is a very important item as respiratory muscle fatigue has been postulated as a cause of ventilatory failure. Dyspnea in patients without pulmonary cause can be due to respiratory muscle weakness. Many factors can affect respiratory muscles and in turn lead to acute or chronic respiratory failure.Allergic rhinitis might have other respiratory sequalae. It might affect respiratory muscle strength.The aim of this study was to study respiratory muscle strength in patients with allergic rhinitis.Twenty seven adult patients with already diagnosed allergic rhinitis were submitted to full medical history taking, complete clinical examination including calculation of BMI, routine laboratory investigations, chest x ray, x ray for nasal sinuses, E.N.T evaluation using all needed procedures to assess the presence or absence of allergic rhinitis and pulmonary function tests including forced vital capacity, slow vital capacity, MIP and MEP in the pulmonary function test unit in Menoufia University Hospitals using Quark PFT3, COSMED, Italy. Ten healthy age and sex matched controls underwent the same testing procedures.Twenty patients of the studied group were females and seven were males. The mean age of the studied patients was 28.97 ± 6.9 years. It was 28.56±9.9 in female patients and 27.98±8.6 in male patients. The mean BMI of all the studied patients was 28.2 ± 4.49. It was 28.52±5.6 in female patients and 27.3±3.5 in male patients. There were 22 of the 27 studied patients having a family history of allergic rhinitis. There were 3 patients with mild allergic rhinitis (2 females and 1 male), 14 patients with moderate allergic rhinitis (10 females and 4 males) and 10 patients with severe allergic rhinitis (8 females and 2 males). When the MIP was compared in the allergic rhinitis group and the control group, there was a significant decrease in MIP in the allergic rhinitis group. When the MEP was compared in the allergic rhinitis group and the control group, there was a significant decrease in MEP in the allergic rhinitis group. When the large and small airway functions were compared in the allergic rhinitis group and the control group, there was a non significant decrease in both functions in the allergic rhinitis group. When the slow vital capacity was compared in the allergic rhinitis group and the control group, there was a non significant decrease in the allergic rhinitis group IVC, EVC, ERV, IRV, VE, Vt and a non significant decrease in the control group Vt/ Ti, Ti/ Ttot and Rf. In patients with allergic rhinitis both MIP and MEP correlated positively with FVC % of predicted, FEV1% of predicted, FEV1/ FVC, FEV1/VC and PEF and negatively with FET 100%.In patients with allergic rhinitis both MIP and MEP correlated positively with FEF 25-75%, MEF 75% and MEF 25%. In patients with allergic rhinitis both MIP and MEP correlated positively with IVC, EVC, ERV, IRV, VE and Vt and negatively with Rf, Ti/Ttot and Vt/ Ti.When MIP and MEP were compared to their predicted values in each age group in allergic rhinitis patients, there was a significant decrease in both of the patients aged 20-30 years and those aged >30-40 years. There was a highly significant decrease in both in patients aged > 40 years. When MIP and MEP were compared to their predicted values in subgroups with different severities of allergic rhinitis, there was a non significant decrease in both in patients with mild allergic rhinitis, there was a significant decrease in MIP in patients with moderate allergic rhinitis and a highly significant decrease in patients with severe allergic rhinitis. When MIP and MEP were compared to their predicted values in both sexes in patients with allergic rhinitis, there was a significant decrease in both males and females. The decrease in female patients was more than the decrease in male patients. Weight, height and BMI correlated positively with MIP and MEP when they were within optimal level in both females and males with allergic rhinitis. Family history of allergic rhinitis correlated negatively with MIP and MEP. Severity of allergic rhinitis correlated negatively with MIP and MEP. MIP correlated positively with MEP. This decrease in respiratory muscle strength in patients with allergic rhinitis may lead to a decrease in quality of life and productivity for these individuals which urge a life long control of such a problem.