الفهرس 
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Abstract
High myopia is defined as refractive error above -6.0 D and axial length above 26 mm. High myopia and its complications are considered to be one of the most significant causes of blindness and visual impairment in young people (Foster & Jiang, 2014).
Optical coherence tomography provides high resolution objective and quantitative measurements of the optic disc parameters and RNFL thickness. The recent introduction of spectral domain- optical coherence tomography technology offers significant advantages over the previous time domain- optical coherence tomography, allowing 3-D imaging of the retina and optic disc with ultra-high acquisition speed and ultra-high resolution (Wojtkowski et al., 2005).
This study aimed to evaluate peripapillary retinal nerve fiber layer thickness in myopic eyes by spectral-domain optical coherence tomography.
This study is a cross sectional study done at the ophthalmology department at the Menoufia university hospital.
Eighty-six eyes of 86 subjects were recruited in this study. All participants have been subjected to Careful full history taking, full ophthalmological examination (best corrected visual acuity, anterior segment evaluation with a slit-lamp biomicroscopy, goldmann applanation tonometry, gonioscopy, dilated fundus examination with a + 90 D fundus lens), refractive state using autorefractometer then spherical equivalent was calculated, axial length measurement in each eye by A-scan ultrasound biometry, automated static perimetry using Octopus perimetry and
Summary
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peripapillary RNFL thickness measurements were obtained by spectralis spectral domain Optical coherence tomography. The participants were categorized into low myopia (SE between -0.5 D to -3.0), moderate myopia (SE between -3.1 D to -5.99 D) and high myopia (SE < -6.0 D). After finishing all subjects’ imaging, statistical analysis has been done.
This study showed that RNFL thickness was lower in the high and moderate myopic eyes compared with low myopic eyes in all quadrants except in temporal quadrant. A highly significant positive correlation was evident between spherical equivalent and RNFL thickness in each quadrant. A highly significant negative correlation between axial length and RNFL thickness in each quadrant.