الفهرس 
Introduction & Review of literatureOnly 14 pages are availabe for public view
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Abstract
To evaluate the effect of the presence of pathogenic bacteria in urine on three bladder cancer genetic markers, isolation and identification of bacteria was performed followed by determination of antimicrobial susceptibility of isolates. Evaluate markers by QPCR. E.Coli is the most predominant bacterial isolates among bladder cancer patients. CK-19 urine marker has low specificity for bladder cancer detection. However, both CK-20 and UPII urine markers show high specificity as they have different expression level for both benign and malignant states. Combined use of UPII and CK-20 could represent a new noninvasive tool for the detection of bladder cancer in urine for patients who have both symptoms of UTI and cancer.