الفهرس 
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Abstract
The aim of this work was to evaluate the role of tranexamate in reduction of blood loss during and after elective caesarean section.
After approval of Local Ethical Committee and with written informed consent, the present study was carried out in El-Shatby Hospital on healthy (116) full term pregnant females aged between 20-35 years old, scheduled for elective Caesarean section under spinal anaesthesia.
Patients were randomly categorized into two equal groups: Group I: Patients were received a bolus injection of one gram of intravenous tranexamic acid diluted in 20 ml of 5% Dextrose solution slowly over five minute at 10 minutes before skin incision , Oxytocin 10 units IV drip was administrated after fetal delivery. Group II: No tranexamic acid was given; oxytocin was administered as in the study group.
In this study:
- There was no significant difference between the two groups.
- The mean gestational age in group I was 39.16±1.39 weeks, while in group II was 39.28±1.28, on comparing the gestational age in the two groups it was found that there was no significant difference between the two groups.
- The Hb level before delivery in the two groups was matched without significant difference, while the level of Hb decreased significantly in group II than group I, also on comparing the two groups after delivery it was found that there was a significant decrease in Hb in group II than I.
- The Ht level before delivery in the two groups was matched without significant difference, while the level of Ht decreased significantly in group II than group I, also on comparing the two groups after delivery it was found that there was a significant decrease in Ht in group II than I.
- Regarding RBCs, and WBCs, it was found that there was no significant difference between the two studied groups regarding RBCs and WBCs.
- Regarding PT, PTT and INR, on comparing the two groups regarding the level of PT, PTT and INR, it was found that there was no significant difference between the two studied groups.
- Regarding amount of blood loss, it was found that the mean amount of blood loss in group I was 314.96±67.81, while in group II was 412.89±84.56, on comparing the two studied groups it was found that there was a significant increase in amount of blood loss in group II than group I.
The aim of this work was to evaluate the role of tranexamate in reduction of blood loss during and after elective caesarean section.
After approval of Local Ethical Committee and with written informed consent, the present study was carried out in El-Shatby Hospital on healthy (116) full term pregnant females aged between 20-35 years old, scheduled for elective Caesarean section under spinal anaesthesia.
Patients were randomly categorized into two equal groups: Group I: Patients were received a bolus injection of one gram of intravenous tranexamic acid diluted in 20 ml of 5% Dextrose solution slowly over five minute at 10 minutes before skin incision , Oxytocin 10 units IV drip was administrated after fetal delivery. Group II: No tranexamic acid was given; oxytocin was administered as in the study group.
In this study:
- There was no significant difference between the two groups.
- The mean gestational age in group I was 39.16±1.39 weeks, while in group II was 39.28±1.28, on comparing the gestational age in the two groups it was found that there was no significant difference between the two groups.
- The Hb level before delivery in the two groups was matched without significant difference, while the level of Hb decreased significantly in group II than group I, also on comparing the two groups after delivery it was found that there was a significant decrease in Hb in group II than I.
- The Ht level before delivery in the two groups was matched without significant difference, while the level of Ht decreased significantly in group II than group I, also on comparing the two groups after delivery it was found that there was a significant decrease in Ht in group II than I.
- Regarding RBCs, and WBCs, it was found that there was no significant difference between the two studied groups regarding RBCs and WBCs.
- Regarding PT, PTT and INR, on comparing the two groups regarding the level of PT, PTT and INR, it was found that there was no significant difference between the two studied groups.
- Regarding amount of blood loss, it was found that the mean amount of blood loss in group I was 314.96±67.81, while in group II was 412.89±84.56, on comparing the two studied groups it was found that there was a significant increase in amount of blood loss in group II than group I.