الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Alloplastic implants have many advantages but the bone healing is one of their challenges. Bioactive glass has interesting properties like bonding to bone, osteoinductivity, osteoconductivity, no cytotoxic effects and high success rate in many clinical uses. Aim of the study: To evaluate the impact of different bioactive glass composition on bone healing. Materials and Methods: 48 male Wistar rats were used. The animals were classified into three main groups, sixteen rats for each group: Group I were subjected to surgical bone defect in the sub mental area of the mandible without using any graft materials. Group II (treated with bioglass 45S5 addition MgO) and Group III (treated with bioglass 45S5 addition ZnO). The rats of each groups were subdivided to be sacrificed after(1, 2, 4 and 6) weeks and examined using light microscope and scanning electron microscope.Results: the histological examination showed that the bone healing was increased with increasing the periods of time the bone healing was enhanced in the samples treated with magnesium than ZnO addition to bioactive glass Conclusions: from the results of the present study, it could be concluded that the bioactive glass enhanced bone matrix formation and maturation of bone trabeculae during bone healing and used as osteoconductive material in bone cavity healing. Moreover; bone healing with bioactive glass in addition of MgO was more accelerated than in addition ZnO to it. |