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العنوان
Chemistry and biology of isolated phenolics from Caesalpinia ferrea leaves (Fabaceae)
المؤلف
Mohammed, Mona Abdalla Mousa
هيئة الاعداد
باحث / مني عبدالله موسي محمد
مشرف / أماني ضياء الدين المسلمي
مشرف / حر عوض الله حسين
مشرف / حمود عبد المعين نوار
الموضوع
isolated phenolics Caesalpinia ferrea leaves (Fabaceae
تاريخ النشر
2015
عدد الصفحات
152P.:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
20/9/2015
مكان الإجازة
جامعة الزقازيق - كلية العلوم - الكيمياء
الفهرس
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Abstract

Three hitherto new di-O-xylosyl-C-glycosyl flavones were isolated from the leaves of C. ferrea. Besides, 11 known compounds were characterized as well. The structures of all compounds were elucidated on the basis of spectroscopic data including 1D and 2D -NMR and HR-ESIMS. On the other hand, the in vitro antioxidant activity using the oxygen radical absorbance capacity (ORAC) method of the extract, and two of the isolated compounds were accomplished; cytotoxicity of the extract using HaCaT cells and in vitro and in vivo hypolipidemic activity of C. ferrea leaves extract revealed hypolipidemic effect.