الفهرس | Only 14 pages are availabe for public view |
Abstract Summary Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies. chronic infections may increase the risk of infertility. Helicobacter pylori infection has been found to be associated with infertility, and PCOS is also one of the most common causes of infertility. To the best of our knowledge, the possible association between H. pylori seropositivity and PCOS has been descriped in the results from a previous study performed in Turkey which showed that about 40% of PCOS cases had positive helicobacter while only 22% of controls had positive helicobacter (Yavasoglu et al., 2009). But yet it has never been investigated in Egypt. So a cross-sectional study was performed in the current work to find if there is an association between Helicobacter Pylori infection and occurrence of Polycystic Ovary Syndrome. The procedure was carried out in Ain Shams University Maternity Hospital at outpatient clinic between a group of 47 PCOS women (mean age, 25.468 ±2.586 years), and an agematched group of controls (47 women; mean age, 25.553 ±2.195 years). The IgG-type antibodies to H. pylori was detected in serum, to aid in the diagnosis of H. pylori infection. H. pylori seropositivity was found to be significantly higher in the PCOS group (PCOS 68.1%; control 25.5%; P = 0.001). So a possible association between H. pylori seropositivity and PCOS is suggested. It is early to state that H. pylori is a new etiological factor for PCOS or the association of PCOS and H. pylori infection is coincidental with these data. Further studies evaluating more subjects are required. |