الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
This prospective study was conducted at Mansoura University SDB unit, and consisted of 212 patients during the period from March 2013 to September 2014 for the investigation of possible SDB, aiming to know the prevalence of OHS in patients attending Mansoura SDB unit and to determine the diagnostic tools for this under diagnosed as well as under estimated serious disease. All patients were subjected to: Clinical evaluation especially for symptoms and signs suggestive of SDB, Berlin questionnaire, ESS scale, and STOP-Bang questionnaire. Laboratory works up. ECG at rest. Chest X-ray. PFTs (Pulse oximeter in sitting position, erect awake ABGs, spirometry). Full night attended PSG.We found that among the 212 patients studied, the mean age was 46.6 ± 11.2, 112 patients (52.8%) were men. The mean value of BMI was 41.74 ± 10.60 kg/m2. The prevalence of SDB in studied cases was 83% and the prevalence of OHS was 13.2% in all studied cases, 14% among obese patients, 16.6% among obese patients with SDB, 19.4% among OSA patients (obese and non-obese), and 20.6% among obese OSA patients. We noticed that obese patients with SDB exhibit statistically significant higher symptoms suggestive of SDB, BMI, STOP-Bang, Berlin questionnaire, PaCO2 and HCO3 values, AHI, ODI, and duration of SpO2 90%, and statistically significant lower SpO2, PaO2, and minimal SpO2% in comparison to obese patients without SDB, while there were no significant differences as regards ESS questionnaire, age, gender, NC, spirometric pulmonary function tests, and basal (awake supine) SpO2. We noticed also that obese patients with SDB had significantly higher comorbidities than obese patients without SDB especially hypertension and dyslipidemia. Our study showed that OHS patients having statistically significant higher SDB symptoms, BMI, Berlin, and STOP-Bang score than obese OSA patients, while there were no significant differences as regards age, gender, Hb %, NC, and ESS questionnaire Conclusion: The overall prevalence of OHS in Mansoura SDB unit is 13.2% in all studied cases, 14% among obese patients, 16.6% among obese patients with SDB, and 20.6% among obese OSA patients.