الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of this study is to examine the relationship between static automated perimetry (SAP) and multifocal ERG (mfERG) findings in different diseases that affect the retina (outer retina: retinitis pigmentosa, inner retina: vascular occlusion), ganglion cells (glaucoma), and optic nerve (glaucoma, optic neuritis). Twenty three eyes of 23 normal control subjects and 60 eyes of 43 patients were enrolled in this prospective comparative non randomized study. They were recruited from the outpatient clinic of Ophthalmology Department, Minia University Hospital. Patients with previous history or presence of detectable spontaneous eye movements were excluded to ensure good fixation during the visual field and electrophysiological testing, as well as patients with corneal, lenticular, or coexisting macular diseases to eliminate any source of error which may result from the potential effects of these conditions on interpreting the test results. All patients underwent full ophthalmological evaluation. mfERG was recorded on the RETI-port/scan21 mfERG version 19-99_D4_7_14E (Roland Consult, Wiesbaden, Germany). Visual field was recorded byusing the Humphrey Field Analyzer (HFAII 745-40398-5.1.2/ 5.1.2, ZEISS, San Leandro, CA, USA), with background illumination of 31.5 abs, stimulus size III, and white colour on white background. Analysis of mfERG data output was performed by ring analysis, quadrant analysis and specialized areas which correspond to localized visual field defects. Evaluation for each obtained averaged response to the amplitude densities between the first negative peak, N1, and the first positive peak, P1 (N1-P1 RAD (response amplitude density), expressed in nano volt per degree square (nV/deg2), and the implicit time of the first positive peak (P1 IT), expressed in milliseconds (ms). The visual field testing data output included: mean deviation, pattern standard deviation, and localized mean deviation. |