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العنوان
T-CELL MARKERS IN LYMPHOMA
المؤلف
ZIDAN, HISHAM EL-SAYED IBARHIM.
هيئة الاعداد
باحث / HISHAM EL-SAYED IBARHIM ZIDAN
مشرف / Ahmad Anwar Shaheen
مشرف / Ahmad Anwar Shaheen
مشرف / Ahmad Anwar Shaheen
الموضوع
Lymphoma. Lymphoma - pathology.
تاريخ النشر
2014.
عدد الصفحات
66 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Biochemistry, Genetics and Molecular Biology (miscellaneous)
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة مدينة السادات - معهد بحوث الهندسة الوراثية - Molecular Diagnostics Department
الفهرس
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Abstract

Lymphoma is a general term for a group of cancers that originate in the lymphatic system. The lymphomas are divided into two major categories: Hodgkin lymphoma and all others lymphomas, called Non-Hodgkin lymphomas.
Aim of this Work is to study the peripheral blood immunophenotypic features of T- lymphomatous cells among patients with Non-Hodgkin Lymphoma (NHL ( attending Menoufyia University Hospitals, compared to normal, by 2-color flow cytometry immunophenotyping.
Materials and Method: The ratios of the subsets of T-lymphocytes and NK cells in the peripheral blood were measured for 25 NHL patients receiving treatment and attending for follow up by the consultant of oncology department, Minoufiya university hospitals. They were compared with those of healthy, age-matched controls. The measurements were accomplished by flow-cytometry.
Results: The patients had significantly decreased ratios of CD4+, CD8+ T-cells and CD4/CD8. With non-significant increased ratio of CD56+ (NK-T cells) comparing to controls.