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Abstract IHD is the most common cardiac disease and is most commonly caused by obstruction of the coronary arteries by atheromatous plaque. CAG remains the standard for identifying the pres¬ence or absence of arterial narrowings related to CAD and provides the most reliable anatomic information. CIN is an important complication of coronary interventions and is most commonly defined as ARF occurring within 48 hr of exposure to intravascular radiographic contrast material that is not attributable to other causes. CIN has many risk factors of which are preexisting impairment of renal function, DM, nephrotoxic drugs, reduction of intravascular volume, advanced age, MM and sepsis Adequate hydration is the simplest and most effective way of protecting renal function. Multiple trials studied the impact of hydration of prevention of CIN. Our study was designed to determine whether LVEDP-guided hydration would be superior to routine hydration in patients at risk for CIN undergoing cardiac catheterization. 200 patients were randomized in a 1:1 fashion to either LVEDP-guided hydration or |