الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
It has been well documented that the molecular framework of a great number of pharmaceuticals and biologically important compounds comprised phenolic or quinonoid moieties. These compounds occupy an important place among the different medicinal groups such as antitumor, antimicrobial, antiprotozoal, antithrombotic/antiplatelet aggregation, antiinflammatory, antidiabetic, antihypertensive and antiarrythmic agents. The various interesting findings found in literature prompted us to synthesize a number of related compounds containing phenolic as well as quinonoid functions. Some of these newly synthesized derivatives were selected by the National Cancer Institute (NCI) to be screened for their anticancer activity while some of them were tested for their antibacterial as well as antifungal activities. Some encouraging results were obtained in both aspects. The present thesis can be subdivided into the following chapters: Chapter 1: Introduction: Introduction presented a brief literature review describing the biologically and pharmaceutically active phenolic derivatives as well as quinones related to benzene and naphthalene nuclei. Chapter 2: Research Objectives: This chapter indicated the rationale upon which the newly synthesized compounds were designed and prepared. Chapter 3: Discussion: In this chapter, the theories upon which the design and synthesis of the intermediates and final compounds was presented. Reference was made to the knowledge available in literature as well as the confirmation of the structures of newly synthesized compounds by different chemical and spectral means. Besides, reference was made to previous efforts made in our laboratory in this field.