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Abstract Trace elements play an important role in metabolism of carbohydrate, proteins, fats and minerals. This will leeds to high effect on growthy production and death rate. Negative effect result in economic losses appear if disturbance occur. Iodine as one of these essential elements, it is important for the building of thyroid hormones which enter in many basal biochemical reactions and feeding; consequently iodine has an effect onproduction of meat, wool, milk and reproductive state of sheep. A total number of 154 Egyptian balady sheep constituted the material of this study. Animals belonged to New Valley (El-Dakhla and El-Kharga (134) and the rest (20) belonged to Assiut Governorate. All animals have been subjected to careful clinical and laboratory methods of examination to ensure their healthy status. Animals have been classified again according to their age, sex and reproductive status (Table 1). The most important clinical signs in sheep suffered from iodine deficiency can be summerized in general weakness, poor condition alopecia, a history of abortion and recently dead lambs and disturbances in reproductive status. The most important biochemical analysis revealed the foUowings: 1 - Low Iodine concentration in blood serum of sheep in El-Dakhla than El-Kharga and the two oasis showed the lowest values when compared with blood serum iodine concentration of sheep at Assiut. 2 - There is a non significant variation between males and females in Iodine concentration in both El-Dakhla and El-Kharga Oasis. 3 - There were non significant differences between good and fairly healthy in ewes in New Valley. 4 - A significant decrease in the iodine concentration in drinking water in New Valley in comparison with their level in drinking water at Assiut. 5 - The investigation showed the influence of Iodine concentration upon the total cholesterol level in blood serum of sheep. 6 - There is a positive correlation between Iodine concentration ill drinking water and its concentration in blood serum of sheep. |