الفهرس 
Post stroke neglectOnly 14 pages are availabe for public view
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Abstract
Stroke results in a variety of neurobehavioral impairments among the most common after right hemisphere stroke are neglect which lead to significant disability and may have a negative impact on recovery from hemiplegia, immobility and overall functional deficits.
UN is described as an impaired ability to attend, respond, or orient to stimuli presented unilaterally, frequently occurring across various sensory systems. Neglect is diagnosed when this impaired ability cannot be attributed to sensory or motor deficits
Several neural models have been proposed to explain post stroke neglect, but no single model can plausibly account for all the complex features of this syndrome, however the most severe and persistent signs of left neglect typically occur after retroRolandic lesions. This may be explained by the architecture of frontoparietal connection.
Conventional tests for UN, such as line bisection and cancellation tests are not necessarily suitable for differentiating between sensory neglect and motor neglect because they involve visual search and a manual response and not recommended to be isolated tests for assessing UN because they have a poor ability to discriminate between UN, cognitive impairment, and constructional apraxia These tests available to measure the functional impact of UN. Although none of the available functional tools can discriminate between sensory neglect and motor neglect, the CBS provides a way of distinguishing personal and spatial neglect.
Assessment of UN using an HMD system may clarify the left neglect area which cannot be easily observed in the clinical evaluation for UN .Also HMD system play an important role in the neuropsychological rehabilitation of unilateral spatial neglect as an evaluation device because HMD can change visual input to fit each patient’s degree of UN.
There is level III evidence that Unilateral Neglect is a complex syndrome which cannot be adequately assessed by a single test alone. The best available evidence to date suggests that a whole battery of tests is more sensitive in detecting neglect. Most importantly, behavioural assessment of neglect in ADLs, using CBS has proved more sensitive than any other single measure and sensitive to change during rehabilitation.
A variety of intervention techniques have been developed in attempts to remediate the behavioral disturbance of neglect such as scanning treatments, which focus on training patients to orient to the neglected side. And use sensory stimulation through use Prism adaptation to enhance perception of the contralesional space.
Transcranial direct current stimulation 5 days /week for 2 weeks was delivered over the posterior parietal cortex of the left hemisphere reducing its inhibitory effect on the contralateral hemisphere, leading to over activation of the contralateral hemisphere and thus additional inhibition of the damaged hemisphere so enhance recovery of patients with visuospatial neglect caused by stroke.
Pharmacological treatment with dopaminergic agonist in post stroke neglect patient enhance of selective attention by increased - dopaminergic activity at D1 receptor that modulates neuronal activity in visual area V4 might provide a possible mechanism by which enhancement of working memory or selective attention. And as adjuvant of physiotherapy has been demonstrated to improve motor function in stroke patients with unilateral weakness .Also cholinesterase inhibitors used for the treatment but there is considerable heterogeneity of its response.