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العنوان
Study of some early diagnostic and prognotic markers in neonatal hypoxic ischemic encephalopathy /
المؤلف
El-Frargy, Mohamed Shawky.
هيئة الاعداد
باحث / Mohamed Shawky El-Frargy
مشرف / Mohamed Ahmed Rowisha
مناقش / Mostafa Mohamed Awny
مناقش / Mohamed Abd-EI-Rhman
الموضوع
Paediatrics.
تاريخ النشر
2010.
عدد الصفحات
120 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة طنطا - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 142

from 142

Abstract

Neonatal Hypoxic ischemic encephalopathy IS considered a common neurological diseases.Main problem in neonatal HIE is not only risk of permanent mental and neurological disabilities but it may extend to affect vital centers and death may occur.Diffusion weighted MRI is a relatively new sequence reflecting molecular motion of water within tissue the water molecules may diffuse\in any direction unless biologic barriers such as cell membrane or pathologic changes limit diffusion, so providing data in tissue integrity .In HIE, DWI shows restricted diffusion (hyperintensity) in basal ganglia, thalami and dorsal brain stem within 24h. after the Ischemia while conventitional Tl and T2 MRI still show no abnormalities.HIE in newborn disturbs mitochondrial energy metabolism and leads to carnitine deficiency