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العنوان
Contribution of Oxytocin and Testosterone
in attenuating atherosclerotic events and
adipose tissue inflammation in male rats/
الناشر
Heba Samy Ibrahim Mohamed Shoukry،
المؤلف
Heba Samy Ibrahim Mohamed ،Shoukry
هيئة الاعداد
باحث / Heba Samy Ibrahim Mohamed ،Shoukry
مشرف / Magda Mahmoud ،El-Hamzawy.
مشرف / Heba Mohamed ،Shawky.
مشرف / Hany ،El Sebaei.
تاريخ النشر
2012.
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب - الفسيولوجى
الفهرس
Only 14 pages are availabe for public view

from 309

from 309

Abstract

Atherosclerosis is considered one of the most common chronic diseases
widely spread in the world nowadays. There are many factors that contribute
to the occurrence and the development of this disease. The most common
factors that predispose to this disease are excess eating high-fat content diet,
decreased physical activity and exposure to social stress in our daily life.
In this study, we aimed to study the effect of high fat diet,
psychological stress and androgen deprivation in the progression of
atherosclerosis. Moreover, we tried to find the impact of testosterone
replacement therapy and oxytocin and their combined effects in attenuating
the events of this disease .
Thus the present study aimed to investigate the role of these hormones
as athero-protective agents through estimation of the serum lipid profile,
inflammatory markers (hs-CRP and IL-6) and serum adiponectin. The gene
expression levels of interleukin-6 , estrogen receptor alpha and adiponectin
receptors 1 &2 were also evaluated.
Key Words:
arbitrary unit – cardiovascular - endothelial cells .