الفهرس | Only 14 pages are availabe for public view |
Abstract Once STAT is activated it translocates into the nucleus and activates target genes as genes encoding for antiapoptotic molecules, such as BCL-XL. EPO also activates phosphorylation of the inhibitor of nuclear factor Kappa B, allowing the release of the transcription factor NF-kB, its translocation into the nucleus and activation of target genes that encode for antiapoptotic proteins. Key word Erythropoietin Reperfusion Apoptosis |